Amitriptyline is a drug that in the past has been used for depression, but now is used mainly for neuropathic (nerve-generated) pain. 

Nortriptyline is closely related to amitriptyline, and is now mainly for neuropathic (nerve-generated) pain. 

Duloxetine is another drug that used to be used for depression, but is known to be active again pain. 

Pregabalin and gabapentin are both drugs that are commonly prescribed for for a wide range of pain conditions. These leaflets give information on doses as well as any side-effects you might see, and how to manage them. 

The leaflets on this page are produced by the Faculty of Pain Medicine of the Royal College of Anaesthetists; Dr Coupe and Dr Souter are both fellows of the Faculty. The leaflets are provided as a service to our patients. They are intended to complement, but not replace a face-to-face discussion about your pain management. 

Information on medications that we prescribe:

Information leaflets